In a large study of all children born in Denmark from December, 1990 to December, 1996 (over 400,000 children), there was no difference in the rate of autism or autism-spectrum disorders in children who received vaccines containing mercury (thimerosal) compared with those who received vaccines without thimerosal. This study adds to the already large amount of research that shows no association between mercury-based preservatives in vaccine and autism or autism-spectrum disorders.